abstract：PURPOSE:The objective of this study was to investigate the predictive value of anti-Mullerian hormone (AMH) on fertilization rate (FR), blastocyst development, embryo quality, the outcome of the pregnancy and the live birth rate (LBR) following in vitro fertilization-embryo transfer (IVF-ET)/intracytoplasmic sperm inje...

journal_title：Journal of assisted reproduction and genetics

authors： Lin WQ,Yao LN,Zhang DX,Zhang W,Yang XJ,Yu R

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:To assesse circulating levels of Anti-Müllerian hormone (AMH) as a predictor of oocyte number and their potential to mature in vitro in both normo-ovulatory (NO) women and in women with Polycystic Ovary Syndrome (PCOS) undergoing in vitro maturation (IVM) treatments. METHODS:We prospectively studied NO women a...

journal_title：Journal of assisted reproduction and genetics

authors： Kedem A,Yerushalmi GM,Maman E,Hemi R,Hanochi M,Hourvitz A

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:This study compared the impact of using the Steiner-Tan pseudo double lumen needle for antral follicle oocyte retrieval to using a conventional non-flushing needle. The Steiner-Tan needle has a much smaller dead space than the needles commonly used for IVM oocyte retrievals. METHODS:This was a retrospective co...

journal_title：Journal of assisted reproduction and genetics

authors： Rose BI,Laky D

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:To assess the effect of assisted hatching (AH) site on the clinical outcomes in vitrified-warmed blastocyst transfer cycles. METHODS:A total of 160 women who underwent vitrified-warmed blastocyst transfer cycles were randomized to either the ICM group (AH performing at the site near the inner cell mess, ICM), ...

journal_title：Journal of assisted reproduction and genetics

authors： Ren X,Liu Q,Chen W,Zhu G,Zhang H

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:To compare the results of intracytoplasmic morphologically selected sperm injection (IMSI) between cycles in which the swim-up (SUP) or the density gradient centrifugation (DGC) techniques were used for sperm preparation. METHODS:We evaluated 70 IMSI cycles performed in women with age ≤ 37 years, undergoing IM...

journal_title：Journal of assisted reproduction and genetics

authors： Borges E Jr,Setti AS,Vingris L,Figueira Rde C,Braga DP,Iaconelli A Jr

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) is a common complex genetic endocrinopathy. It has high heritability, and twin studies indicate that it is a complex polygenic disorder. Searching for major genes of PCOS is crucial to clarify its molecular pathogenesis. A previous genome-wide association study in Chinese wom...

journal_title：Journal of assisted reproduction and genetics

authors： Fu L,Zhang Z,Zhang A,Xu J,Huang X,Zheng Q,Cao Y,Wang L,Du J

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:Embryo cryopreservation after triggering oocyte maturation with GnRH agonist (GnRHa) in GnRH antagonist protocols has been proposed to prevent ovarian hyperstimulation syndrome (OHSS). However, a small percentage of patients still developed severe OHSS. The purpose of the study was to investigate the efficacy o...

journal_title：Journal of assisted reproduction and genetics

authors： Lin YH,Huang MZ,Hwang JL,Chen HJ,Hsieh BC,Huang LW,Tzeng CR,Seow KM

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:Surgical repair of varicocele has long been a procedure to correct spermatogenesis. However, the outcome has been reported to be inadequate. We combined varicocelectomy with supplement therapy to evaluate the concurrent effect of these procedures. METHODS:A prospective randomized controlled study was undertake...

journal_title：Journal of assisted reproduction and genetics

authors： Azizollahi G,Azizollahi S,Babaei H,Kianinejad M,Baneshi MR,Nematollahi-mahani SN

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To explore that it is necessary to routinely detect chromosomes in fertile couples, we detected peripheral blood lymphocyte karyotype in 14965 infertile couples living in Central China and analyzed the incidence and type of chromosomal anomaly. METHODS:G-banding karyotype analysis of peripheral blood lymphoc...

journal_title：Journal of assisted reproduction and genetics

authors： Liu Y,Kong XD,Wu QH,Li G,Song L,Sun YP

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To investigate two of the most studied estrogen receptor alpha polymorphisms (PvuII and XbaI) in combination, in order to evaluate their impact on an ART program outcome. METHODS:203 normally ovulating women who underwent IVF or ICSI treatment were genotyped for PvuII and XbaI polymorphisms in ESR1 intron 1 us...

journal_title：Journal of assisted reproduction and genetics

authors： Anagnostou E,Malamas F,Mavrogianni D,Dinopoulou V,Drakakis P,Kallianidis K,Loutradis D

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To generate novel, objective variables that resemble embryo quality and relate them to ongoing implantation, using multilevel imaging of single-transferred embryos. METHODS:Retrospective analysis of multilevel images of 659 day 3 single-transferred embryos. Each embryo was photographed on seven different level...

journal_title：Journal of assisted reproduction and genetics

authors： Vergouw CG,Al Nofal M,Kostelijk EH,Rooth H,Hompes PG,Schats R,Lambalk CB

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To avoid inducing a state of oxidative stress (OS), assisted reproductive technologies (ART) must maintain a balance of reactive oxygen species (ROS) and antioxidants during the in vitro culture of oocytes. However, oocyte requirements and tolerance thresholds for ROS during in vivo development are still unclea...

journal_title：Journal of assisted reproduction and genetics

authors： Hennet ML,Yu HY,Combelles CM

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:Spermatogonial stem cells are affected by the interactions of extrinsic signals produced by components of the microenvironment niche, in addition to the chemical and physical properties of the extracellular matrix. Therefore, this study was initiated to assess the interaction of these cells on a synthetic nanof...

journal_title：Journal of assisted reproduction and genetics

authors： Shakeri M,Kohram H,Shahverdi A,Shahneh AZ,Tavakolifar F,Pirouz M,Shahrebabak HM,Koruji M,Baharvand H

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:Histone H3 lysine 9 (H3K9) methylation plays an important role in the regulation of preimplantation embryo development. G9a has been reported to be a major H3K9mono (m1)/dimethylation(m2) methyltransferase and to contain nuclear localization signals. This study was performed to investigate the correlation betwe...

journal_title：Journal of assisted reproduction and genetics

authors： Li B,Tang N,Chen S,Li X,Huang X,Wang X,Sun F

更新日期：2013-03-01 00:00:00

abstract：PROBLEM:Numerous lines of evidence implicate Apolipoprotein E (Apo E) in lipid metabolism during pregnancy. Hence, a role for its polymorphism has been envisaged in recurrent pregnancy loss (RPL) considering major structural and functional differences between different Apo E genotypes. METHOD OF STUDY:A case control s...

journal_title：Journal of assisted reproduction and genetics

authors： Asgari N,Akbari MT,Zare S,Babamohammadi G

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:To evaluate the efficiency of an original slow freezing protocol on the quality and function of human ovarian cortex. METHODS:Human ovarian tissues were cryopreserved using a freezing medium supplemented with propanediol and raffinose as cryoprotectants and antioxidants (L-glutamine, taurine). Samples were the...

journal_title：Journal of assisted reproduction and genetics

authors： Sanfilippo S,Canis M,Romero S,Sion B,Déchelotte P,Pouly JL,Janny L,Smitz J,Brugnon F

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:We previously reported associations between trace concentrations of Hg, Cd and Pb in blood and urine and reproductive outcomes for women undergoing in-vitro fertilization (IVF). Here we assess measurements in single follicular fluid (FF) specimens from 46 women as a presumably more relevant marker of dose for r...

journal_title：Journal of assisted reproduction and genetics

authors： Bloom MS,Kim K,Kruger PC,Parsons PJ,Arnason JG,Steuerwald AJ,Fujimoto VY

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:To evaluate the relationship between oocyte dysmorphisms and IMSI outcomes METHODS:Data of IMSI cycles performed in 332 patients were included in this study. Patients were included only if presented more than four and less than 30 oocytes upon oocyte retrieval. Patients who underwent IMSI were matched, concern...

journal_title：Journal of assisted reproduction and genetics

authors： Setti AS,Braga DP,Figueira RC,Iaconelli A Jr,Borges E Jr

更新日期：2012-11-01 00:00:00

abstract：:Embryos diagnosed as abnormal in Preimplantation Genetic Diagnosis (PGD) cycles are useful for the establishment of human Embryonic Stem Cells (hESC) lines with genetic disorders. These lines can be helpful for drug screening and for the development of new treatments. Vitrification has proved to be an efficient method...

journal_title：Journal of assisted reproduction and genetics

authors： Aran B,Sole M,Rodriguez-Pizà I,Parriego M,Muñoz Y,Boada M,Barri PN,Izpisúa JC,Veiga A

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:To compare the efficacy of intrafollicular sperm injection (IFI) versus intrauterine insemination (IUI) in the treatment of subfertility. METHODS:38 couples suffering primary or secondary subfertility contributed a total of 47 IUI or IFI cycles, 26 by IUI and 21 by IFI. Folliculogenesis, ovulation triggering, ...

journal_title：Journal of assisted reproduction and genetics

authors： Lucchini C,Volpe E,Tocci A

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:Standard semen parameters are poor predictors of fertility potential. To date, apart from, paternal karyotyping sperm factors are not evaluated in recurrent pregnancy loss (RPL), only recent studies have emphasized the role of sperm factors in early embryonic development as sperm transcribes genes critical for ...

journal_title：Journal of assisted reproduction and genetics

authors： Kumar K,Deka D,Singh A,Mitra DK,Vanitha BR,Dada R

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:Apart from freezing/thawing related cryodamage, several additional factors have been identified as major players in the reduction of success rates after frozen embryo transfers. The post-thaw culture is particularly relevant as it may amplify environmental influences over a stressed embryo. In the present study...

journal_title：Journal of assisted reproduction and genetics

authors： Rato ML,Gouveia-Oliveira A,Plancha CE

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:Retinal pigment epithelium cells derived from human embryonic stem cells (ESCs) could be useful for restoring retinal function in age-related macular degeneration. However the use of non-human feeder cells to support the growth of ESCs for clinical applications raises the concern of possible contamination becau...

journal_title：Journal of assisted reproduction and genetics

authors： Zhang YS,Lu ZY,Yu Y,Li XR,Li WB,Wang YN,Geng Y

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:Preimplantation Genetic Diagnosis (PGD) has proven to be a useful reproductive option for carriers of some chromosome rearrangements. The data presented in this study compares the impact of one versus two blastomere biopsy on the likelihood of achieving a PGD result, as well as the effect on subsequent embryo d...

journal_title：Journal of assisted reproduction and genetics

authors： Brodie D,Beyer CE,Osborne E,Kralevski V,Rasi S,Osianlis T

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:To determine the percentage of unbalanced spermatozoa and an interchromosomal effect in two carriers of balanced translocations t(13;15)(q32;q26) and t(13;15)(q32;p11.2). METHODS:Sperm nuclei analysis by fluorescent in situ hybridization for detection of percentage of unbalanced spermatozoa and sperm with diso...

journal_title：Journal of assisted reproduction and genetics

authors： Kasikova K,Vozdova M,Prinosilova P,Gaillyova R,Hanakova M,Rubes J

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:To demonstrate that a euploid embryo derived from an oocyte with reciprocal aneuploid polar bodies is capable of producing a chromosomally normal child. METHODS:A case report of maternal MI error compensation where single nucleotide polymorphism (SNP) microarray based comprehensive chromosome screening (CCS) w...

journal_title：Journal of assisted reproduction and genetics

authors： Scott RT Jr,Treff NR,Stevens J,Forman EJ,Hong KH,Katz-Jaffe MG,Schoolcraft WB

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:To evaluate if several genetic loci that are associated with variation in normal menopause age and early menopause can account for a poor response to controlled ovarian stimulation. METHODS:A total of 71 patients age ≤35 years old who were undergoing intracytoplasmic sperm injection were genotyped for four gen...

journal_title：Journal of assisted reproduction and genetics

authors： Setti AS,Cortezzi SS,Figueira Rde C,Martinhago CD,Braga DP,Iaconelli A Jr,Borges E Jr

更新日期：2012-05-01 00:00:00

abstract：BACKGROUNDS:While XXY aneuploidy is the most common disorder of sex chromosomes in men, complex chromosomal rearrangements (CCRs) are rare in humans. CASE DESCRIPTION:Here we describe clinical and cytogenetic findings in a male referred to our cytogenetic laboratory by an infertility clinic. The patient's age was 35 a...

journal_title：Journal of assisted reproduction and genetics

authors： Mahjoubi F,Razazian F

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To determine Vit E effect on the treatment outcomes of women with unexplained infertility undergoing controlled ovarian stimulation and intrauterine insemination (IUI). METHODS:The study group (Group A, n053) underwent controlled ovarian stimulation with clomiphene citrate with Vit E administration, 400 IU/day...

journal_title：Journal of assisted reproduction and genetics

authors： Cicek N,Eryilmaz OG,Sarikaya E,Gulerman C,Genc Y

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:Approximately 8% of couples attempting to conceive are infertile and male infertility accounts for approximately 50% of infertility among couples. Up to 25% of males with non-obstructive infertility have chromosomal abnormalities and/or microdeletions of the long arm of the Y-chromosome. These are detected by c...

journal_title：Journal of assisted reproduction and genetics

authors： Hofherr SE,Wiktor AE,Kipp BR,Dawson DB,Van Dyke DL

更新日期：2011-11-01 00:00:00

abstract：:Sperm is not a simple carrier of paternal genetic information but its role extends clearly beyond fertilization. Integrity of sperm genome is an essential pre-requisite for birth of healthy offspring and evaluation of sperm should entail DNA integrity analysis. DNA integrity analysis is a better diagnostic and prognos...

journal_title：Journal of assisted reproduction and genetics

authors： Shamsi MB,Imam SN,Dada R

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:The number of women attempting to conceive between the ages of 36 and 44 has increased significantly in the last decade. While it is well established that women's reproductive success dramatically declines with age, the underlying physiological changes responsible for this phenomenon are not well understood. Wi...

journal_title：Journal of assisted reproduction and genetics

authors： Bentov Y,Yavorska T,Esfandiari N,Jurisicova A,Casper RF

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:To determine the expression of SMAD transcripts in human granulosa cells. METHODS:Luteinized mural granulosa cells were harvested from forty women undergoing oocyte retrieval, and RNAs were isolated. SMAD expression levels were determined by polymerase chain reaction (PCR) and quantitative real-time PCR (q-RTP...

journal_title：Journal of assisted reproduction and genetics

authors： Kuo FT,Fan K,Ambartsumyan G,Menon P,Ketefian A,Bentsi-Barnes IK,Pisarska MD

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:To understand the molecular basis of sperm-motility and to identify related novel motility biomarkers. METHODS:Two-dimensional electrophoresis (2DE) followed by Reverse-phase-nano-high-performance liquid chromatography-electrospray ionization tandem mass spectrometry (RP-nano-HPLC-ESI-MS/MS) were applied to es...

journal_title：Journal of assisted reproduction and genetics

authors： Chao HC,Chung CL,Pan HA,Liao PC,Kuo PL,Hsu CC

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:To determine common molecular markers between endometriosis and ovarian cancer. METHODS:Patients included women who underwent laparoscopic excision of ovarian endometriotic lesions (n = 7), healthy non-pregnant women with normal pelvises, who underwent excision of normal peritoneum (n = 7). Two epithelial ovar...

journal_title：Journal of assisted reproduction and genetics

authors： Meng Q,Sun W,Jiang J,Fletcher NM,Diamond MP,Saed GM

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:The length of GT-repeats polymorphic region in the promoter of human Heme oxygenase-1 gene (HO-1) alters the level of its transcriptional activity in response to oxidative stresses. Decreased level of HO-1 protein in the seminal plasma has been reported to be associated with oligospermia and azoospermia in male...

journal_title：Journal of assisted reproduction and genetics

authors： Siasi E,Aleyasin A,Mowla SJ,Sahebkashaf H

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:To evaluate clinical outcomes of frozen-thawed embryo transfer cycles when one or two blastocysts are transferred. METHODS:Retrospective chart review RESULTS:Two hundred forty-three frozen blastocyst transfer (FBT) cycles were analyzed. Clinical pregnancy rate (50.4% vs. 34.7%), live birth rate (45.8% vs. 30....

journal_title：Journal of assisted reproduction and genetics

authors： Berin I,McLellan ST,Macklin EA,Toth TL,Wright DL

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:To identify differentially expressed microRNAs (miRNAs) and expression patterns of specific miRNAs during meiosis in human oocytes. MATERIALS AND METHODS:To identify differentially expressed miRNAs, GV oocytes and MII oocytes matured at conventional FSH levels (5.5 ng/ml) were analyzed by miRNA microarray. Rea...

journal_title：Journal of assisted reproduction and genetics

authors： Xu YW,Wang B,Ding CH,Li T,Gu F,Zhou C

更新日期：2011-06-01 00:00:00

abstract：:In an attempt to assess the effect of perfluorinated compounds (PFC) on oocytes quality and fertilization rate, we studied follicular fluid (FF) PFC levels in 18 patients undergoing IVF-ET cycles. A significant correlation (R = 0.75; P < 0.001) was observed between FF PFC levels and fertilization rate. Moreover, patie...

journal_title：Journal of assisted reproduction and genetics

authors： Governini L,Orvieto R,Guerranti C,Gambera L,De Leo V,Piomboni P

更新日期：2011-05-01 00:00:00

abstract：AIM:To investigate follicular fluid IGF 1, IGFBP 3 and their effects on IVF outcome in patients using different gonadotropins. MATERIALS AND METHODS:This prospective study was performed among 92 IVF patients who were categorized according to IVF pregnancy outcome. Two groups were formed as Group 1 : pregnant, Group 2:...

journal_title：Journal of assisted reproduction and genetics

authors： Genc G,Yilmaz N,Uygur D,Dogan M,Mollamahmutoglu L

更新日期：2011-05-01 00:00:00